Where binding Unbound to *:53, set "interface-automatic: yes" so replies are sourced from the correct IP. Ideally this should always work this way, but setting this causes Unbound to bind to *:53, which shouldn't happen where specific interfaces are chosen. Ticket #4111
Related issues
Bug #4111: Unbound replies using wrong source IP when bound to *
Where binding Unbound to *:53, set "interface-automatic: yes" so replies are sourced from the correct IP. Ideally this should always work this way, but setting this causes Unbound to bind to *:53, which shouldn't happen where specific interfaces are chosen. Ticket #4111